Establishing the Cause of Nephrotic Syndrome in an Unlikely Scenario – A Case Report
1 Doctoral School of Medicine, “Victor Babes” University of Medicine and Pharmacy, 300041 Timișoara, Romania
2 Department of Diabetes, "Pius Brinzeu" Emergency Hospital, 300723 Timisoara, Romania
3 Centre for Molecular Research in Nephrology and Vascular Disease, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania
4 Second Department of Internal Medicine, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania
5 Department of Nephrology, "Pius Brinzeu" Emergency Hospital, 300723 Timisoara, Romania
* Author to whom correspondence should be addressed.
Received: 13 Dec 2024 / Accepted: 27 Dec 2024 / Published: 27 Dec 2024
Abstract
Abstract: Chronic hyperglycemia in the context of type 2 diabetes predisposes patients to developing diabetic chronic kidney disease. The following clinical case covers a 55-year old patient with a longstanding history of type 2 diabetes and essential hypertension admitted for typical symptoms of uncontrolled diabetes to the Diabetes Department of "Pius Brinzeu" Emergency Hospital. Clinical evaluation and laboratory results pointed to the diagnosis of nephrotic syndrome, however, did not present at first a clear cause for such high levels of proteinuria. This report follows the meticulous logic needed in order to establish the cause of nephrotic syndrome, all the way to a justifiable renal biopsy. Once diabetic nephropathy was established, adding treatment with an SGLT2i was considered a valid treatment option due to its antiproteinuric effects.
Keywords: empagliflozin; nephrotic syndrome; type 2 diabetes
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This is an open access article distributed under the Creative Commons Attribution
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CITE
Herascu, A.; Avram, V.; Grosu, I.; Gaita, L.; Braha, A.; Sima, A.; Timar, B. Establishing the Cause of Nephrotic Syndrome in an Unlikely Scenario – A Case Report. Timisoara_Med 2024, 2024, 27.
Herascu A, Avram V, Grosu I, Gaita L, Braha A, Sima A, Timar B. Establishing the Cause of Nephrotic Syndrome in an Unlikely Scenario – A Case Report. Timisoara Medical Journal. 2024; 2024(2):27.
Herascu, Andreea; Avram, Vlad; Grosu, Iulia; Gaita, Laura; Braha, Adina; Sima, Alexandra; Timar, Bogdan. 2024. "Establishing the Cause of Nephrotic Syndrome in an Unlikely Scenario – A Case Report." Timisoara_Med 2024, no. 2: 27.
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