Current Perspectives in MODY Management—A Narrative Review
1 Department of Diabetology, Emergency Clinical County Hospital, 540136 Targu Mures, Romania; (O.D.); (B.I.K.); (R.A.S.); (M.C.T.)
2 Department of Internal Medicine I, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology, 540139 Targu Mures, Romania
* Correspondence:
* Author to whom correspondence should be addressed.
Received: 8 Oct 2021 / Revised: 13 Dec 2021 / Accepted: 13 Dec 2021 / Published: 24 Dec 2021
Abstract
Maturity-onset diabetes of the young (MODY) is associated with familially inherited monogenic diabetes. It is characterized by genetic mutations leading to pancreatic β-cell dysfunction and subsequent insulin production. Clinical features of MODY include young-onset hyperglycemia associated with a lack of beta cell autoimmunity or insulin resistance. Glucose-lowering agents are the main therapeutic options for MODY. In this review, we have outlined the particular aspects of the most common types of MODY in order to assist clinical practitioners in this field.
Keywords: MODY; genetic mutations; oral antidiabetics
OPEN ACCESS
This is an open access article distributed under the Creative Commons Attribution
License which permits unrestricted use, distribution, and reproduction in any medium,
provided the original work is properly cited. (CC BY 4.0).
CITE
Deteșan, O.; Custură, L.M.; Kovács, B.I.; Schmiedt, R.A.; Tilinca, M.C. Current Perspectives in MODY Management—A Narrative Review. Timisoara_Med 2021, 2021, 4.
Deteșan O, Custură LM, Kovács BI, Schmiedt RA, Tilinca MC. Current Perspectives in MODY Management—A Narrative Review. Timisoara Medical Journal. 2021; 2021(2):4.
Deteșan, Oana; Custură, Lucia Mihaela; Kovács, Brigitta Irén; Schmiedt, Reka Annamaria; Tilinca, Mariana Cornelia. 2021. "Current Perspectives in MODY Management—A Narrative Review." Timisoara_Med 2021, no. 2: 4.
Not implemented
SHARE
