@Article{
AUTHOR = {Pusztai, Agneta Pusztai and Daescu, Ecaterina Daescu and Rosu, Luminioara Rosu and Haivas, Carmen Camelia Haivas and Petrescu, Codruta Petrescu and Zahoi, Delia Zahoi},
TITLE = {Liver Segmentation - Morphological Basis for PET-CT Evaluation of Liver Secondary Determinations},
JOURNAL = {Timisoara Medical Journal},
VOLUME = {2024},
YEAR = {2024},
NUMBER = {2},
PAGES = {--},
URL = {https://tmj.jams.pub/article/2024/2/290},
ISSN = {1583-526X},
ABSTRACT = {The purpose. 
Establishing through a morpho-functional study, which is the most frequent location of metabolically active liver metastases, highlighted by PET-CT correlated with the histological type, in patients with relapses.

Materials and methods. 
The study material was represented by the iconography of 127 patients investigated by PET-CT (Affidea Timișoara), who had presumptive diagnoses of secondary liver determinations.
PET-CT investigation reveals the three-dimensional distribution of radioactivity based on annihilation photons emitted by radiotracers labeled with a positron emitter (F18-FDG). The imaging analysis was complemented by the measurement of SUVlbm, the maximum uptake intensity of the radiotracer.

Results. 
The PET-CT examination revealed metabolically active liver lesions in 108 cases.
In 95 cases (87.96%), metabolically active multiple nodular lesions were revealed, in different degrees of uptake. 
Multiple metastases were highlighted at the following levels: RHL - 43 cases; LHL - 21 cases; disseminated - 31 cases.
In 13 cases (12.04%), the metastases were solitary, starting point: breast (4xBC), bronchopulmonary (3xBPC), cutaneous malignant melanoma (2xMM), colorectal (3xCRC), pancreatic (1xPC).
In the case of solitary liver metastases, the segmental location was as follows:
•	S-I: 1 case (1 x PC)
•	S-II: 1 case (1 x BC)
•	S-III: 2 cases (1 x BC + 1 x BPC)
•	S-IV: 1 case (1 x BC)
•	S-VI: 5 cases (2 x BPC + 2 x CRC + 1 x MM)
•	S-VII: 3 cases (1 x BC + 1 x CRC + 1 x MM).

Conclusions. 
• Most frequently, multiple liver metastases were highlighted at the RHL level - 43 cases (45.26 %).
• In 13 cases (12.04%) the lesions were solitary, having the starting point, most frequently, at the breast level - 4 cases (30.77%)
• The maximum value SUVlbm=13.7 was highlighted in the case of the single metastasis of MM, located at the S-VI level.},
DOI = {10.35995/tmj20240220}
}